8-Hydroxy-naphthalene-1-carboxylic acid methyl ester

8-Hydroxy-naphthalene-1-carboxylic acid methyl ester - Names and Identifiers

Name	Methyl 8-hydroxy-1-naphthoate
Synonyms	Methyl 8-hydroxy-1-naphthoate methyl 8-hydroxynaphthalene-1-carboxylate Methyl 8-hydroxy-1-naphthalenecarboxylate 8-Hydroxy-naphthalene-1-carboxylic acid methyl ester 1-Naphthalenecarboxylic acid, 8-hydroxy-, methyl ester Methyl 8-hydroxynaphthalene-1-carboxylate, 1-Hydroxy-8-(methoxycarbonyl)naphthalene
CAS	5247-86-9

8-Hydroxy-naphthalene-1-carboxylic acid methyl ester - Physico-chemical Properties

Molecular Formula	C12H10O3
Molar Mass	202.21
Density	1.264±0.06 g/cm3(Predicted)
Melting Point	59-62℃
Boling Point	368.5±15.0 °C(Predicted)
pKa	8.63±0.40(Predicted)
Storage Condition	Sealed in dry,Room Temperature

8-Hydroxy-naphthalene-1-carboxylic acid methyl ester - Introduction

Methyl 8-hydroxy-1-naphthoate(Methyl 8-hydroxy-1-naphthoate) is an organic compound with the chemical formula C12H10O3. The following is a description of its nature, use, formulation and safety information:

Nature:
-Appearance: Methyl 8-hydroxy-1-napthoate is a white to pale yellow solid.
-Solubility: Soluble in organic solvents such as ethanol, ether and dimethyl sulfoxide.
-Melting point: about 150-152°C.
-Density: about 1.23g/cm³.

Use:
-Cosmetics: Methyl 8-hydroxy-1-napthoate can be used as a sunscreen in cosmetics to provide ultraviolet (UV) protection.
-Drugs: It can also be used as an intermediate for certain drugs, such as amoxicillin, tromethamine benzoate, etc.
-Research field: In organic chemistry research, this compound can be used as a reducing agent, a catalyst for hydrogenation reactions or a substrate for oxidation reactions.

Preparation Method:
The synthesis of Methyl 8-hydroxy-1-naphthoate is usually obtained by reacting 8-hydroxy-1-naphthoic acid with methanol under alkaline conditions. In the reaction, methanol can be catalyzed by an alkaline catalyst such as sodium hydroxide or potassium hydroxide to form Methyl 8-hydroxy-1-napthoate.

Safety Information:
- Methyl 8-hydroxy-1-napthoate may be irritating to the eyes and skin, and should be rinsed with plenty of water immediately after contact. Care must be taken to avoid inhalation of dust and skin contact.
-If ingested by accident, you should immediately seek the help of a hospital doctor and show the safety data sheet (SDS) of the compound.
-Operate in a well-ventilated area and wear appropriate protective equipment, such as gloves and glasses.
-Store and handle the compound properly and avoid contact with flammable substances.
-Before use or disposal, be sure to carefully read and follow the relevant safety information for the compound.

Last Update：2024-04-09 15:17:58